>>437
血液脳関門さえ通過すれば効果があるらしい
https://www.sciencedaily.com/releases/2010/10/101001163342.htm

でもヒトやマウスでは通過しない
http://dmd.aspetjournals.org/content/34/12/1945.full
>The brain penetration of imatinib is low in human and mouse (Dai et al., 2003; Le Coutre et al., 2004).

http://www.ncbi.nlm.nih.gov/pubmed/12604685
http://www.ncbi.nlm.nih.gov/pubmed/14658008