ほらほらじゃろさん大好きなケトン体ですよー

https://www.ncbi.nlm.nih.gov/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Click%20on%20image%20to%20zoom&;p=PMC3&id=4530073_nihms-696769-f0002.jpg

Ketogenesis mainly occurs in the mitochondria of liver cells, which normally converts acetyl-CoA to ketone bodies
via HMG-CoA as a result of fatty acid breakdown to generate energy when glucose levels in the blood are low. HMGCL converts HMG-CoA to acetyl-coA and a ketone body,
acetoacetate (AA), which can be further converted to two other ketone bodies,
including D-β-hydroxybutyrate (3-HB) and acetone (Balasse and Fery, 1989; McPherson and McEneny, 2012). We found that HMGCL is upregulated in a
group of BRAF V600E-expressing human melanoma cell lines compared to cells expressing BRAF WT (Figure 2A left), and in the immortalized melanocyte Mel-ST cells expressing BRAF V600E but not BRAF WT (Figure 2A right).